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GENERAL PUBLIC
UNDERSTANDING GENETICS
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TEST YOUR KNOWLEDGE
 
Test Your Knowledge

 
1.
 
The human genome is
a. Made of RNA
b. 3 billion base pairs in length
c. Over one million genes
d. The same in every person
 
2.
 
Put these terms in order of size, largest to smallest, based on the structures or ideas they represent:
a. Nucleotide, DNA, chromosome, Genome, Gene
b. DNA, gene, chromosome, genome, nucleotide
c. Chromosome, DNA, gene, genome, nucleotide
d. Genome, chromosome, gene, DNA, nucleotide
 
3.
 
Which of these statements about DNA is not true?
a. DNA contains the instructions needed to make proteins.
b. The amount of DNA that differs from one person to another is less than 1%.
c. DNA controls how much of a protein will be made and when it will be made.
d. DNA is made up of many chromosomes.
 
4.
 
Inheritance patterns may be classified into the following categories EXCEPT:
a. Autosomal dominant
b. Autosomal recessive
c. Complex
d. Mitochondrial
 
5.
 
Common, complex diseases, such as heart disease, are thought to be caused by ____________.
a. one or more disease susceptibility genes
b. the environment
c. the interaction of susceptibility genes and the environment
 
6.
 
Autosomal recessive conditions:
a. Are often associated with deficient enzyme activity.
b. Always contain the same mutation in both genes.
c. Are more variable than autosomal dominant conditions.
d. Are likely to affect the children of affected individuals.
 
7.
 
Differing responses among individuals to the same type or dose of medicine may have a genetic basis.
a. True
b. False
 
8.
 
Medicine Response Tests are being used to predict how a person will react to a drug.
a. True
b. False
 
9.
 
To establish ethical standards, GSK ___________________.
a. consults experts in the field
b. considers guidelines from national and international bodies
c. reviews its ethics policies on an ongoing basis
d. all of the above
 
10.
 
Which of these statements about genetic variation is not true?
a. The DNA sequence of all humans is almost identical.
b. Alleles are different forms of the same gene.
c. Genetic mutations are usually fatal.
d. SNPs (single nucleotide polymorphisms) are the most common form of genetic variation.
 
11.
 
DNA consists of
a. nucleotides
b. chromosomes
c. two twisting sugar-phosphate backbones
d. chromatids
e. a and d
 
12.
 
Most genetic differences among humans are accounted for by
a. different genomes
b. different sugar-phosphate backbones in the DNA
c. different base pair sequences
d. different genetic materials
 
13.
 
Identify the correct statements:
a. Only I is true.
b. I and III are true.
c. II and III are true.
d. All are true.
 
14.
 
An egg cell contains
a. Half the normal number of chromosomes (23)
b. All of the mother's alleles
c. No sex chromosomes
d. A and B
 
15.
 
If you are male, your Y chromosome comes from
a. your mother
b. your father
c. either your mother or father
d. a mutation
 
16.
 
Pick the false statement about susceptibility genes.
a. They are the single cause of many diseases.
b. They may affect when a disease occurs.
c. They may how a disease progresses over time.
d. They may help protect against disease.
 
17.
 
The genetic differences between people who have a disease and those who don't are too small to be detected using current technology.
a. True
b. False
 
18.
 
Pick the false statement about SNPs.
a. They are one type of genetic marker.
b. They are used to confirm who is a child's father.
c. They occur frequently throughout the human genome.
d. They can be used to predict a person's risk of some diseases or a person's response to a medicine.
 
19.
 
The SNP Consortium is
a. a government agency associated with the Human Genome Project.
b. releasing a frequently updated high-density human SNP map into the public domain.
c. collecting data about SNPs and human diseases.
d. identifying human genes.
 
20.
 
On average, about 1 in every 5,000 possible new medicines eventually is approved and marketed.
a. True
b. False